Disseminated plantar lentigines associated with Peutz-Jeghers syndrome

A 10-year-old boy had a family history that included a father and brother with Peutz-Jeghers syndrome. His current illness began at 2 years of age with the presence of blackish hyperchromatic spots of approximately 3 mm in diameter on his lip area that increased in number and diameter (Fig. 1). From the age of 6 years hyperchromic spots with similar characteristics appeared on his palms and on the soles of his feet, where they were present on the areas of the toes, the metatarsi, and the heels (Fig. 2). Imaging and endoscopic studies confirmed the presence of polyps in the colon and small bowel (Fig. 3). The histopathology study reported that they were of the hamartomatous type (Fig. 4). Peutz-Jeghers syndrome is characterized by the presence of numerous hamartomatous polyps distributed