Recurrencia sintomática al descontinuar inhibidores de la bomba de protones durante la monitorización inalámbrica del pH esofágico Bravo ® en pacientes con enfermedad por reflujo gastroesofágico

The article by Shey et al. in the current issue evaluates the degree of symptomatic recurrence of gastroesophageal reflux disease (GERD) after the suspension of proton pump inhibitors (PPIs) and its correlation with symptoms during ambulatory pH monitoring with the Bravo ® wireless capsule. In this retrospective review, the authors showed that the patients with a shorter period of PPI suspension presented with greater symptomatology and the patients whose symptoms worsened during the pH monitoring study presented with greater acid exposure. A total of 55.1% of the patients experienced symptom worsening that was correlated with a percentage of time with pH under 4. The authors called their test an inverse PPI trial and discussed its possible role in predicting the cases that could present with a positive ambulatory wireless pH monitoring study. The correlation was adequate, but just slightly over half of the patients presented with said worsening and only approximately 60% of the patients with symptom exacerbation had a pathologic pH study. PPI trial sensitivity