Noncompaction and embolic myocardial infarction: The importance of oral anticoagulation | Zendy

Giovanni Pulignano | Zendy; Maria Denitza Tinti | Zendy; Stefano Tolone | Zendy; Carmine Musto | Zendy; Lucia De Lio | Zendy; Paolo Giuseppe Pino | Zendy; Giovanni Minardi | Zendy; Roberto Violini | Zendy; Massimo Uguccioni | Zendy

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Noncompaction and embolic myocardial infarction: The importance of oral anticoagulation

Author(s) -

Giovanni Pulignano,

Maria Denitza Tinti,

Stefano Tolone,

Carmine Musto,

Lucia De Lio,

Paolo Giuseppe Pino,

Giovanni Minardi,

Roberto Violini,

Massimo Uguccioni

Publication year - 2015

Publication title -

revista portuguesa de cardiologia

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.266

H-Index - 26

eISSN - 2174-2030

pISSN - 0870-2551

DOI - 10.1016/j.repc.2015.01.014

Subject(s) - medicine , cardiology , ventricle , myocardial infarction , thrombus , thrombosis , embolism , heart failure , left ventricular thrombus

Left ventricular noncompaction (LVNC) is characterized by left ventricular (LV) hypertrabeculations and is associated with heart failure, arrhythmias and embolism. We report the case of a 67-year-old LVNC patient, under oral anticoagulation (OAC) therapy for apical thrombosis. After she discontinued OAC, the thrombus involved almost the whole of the left ventricle; in a few months her condition worsened, requiring hospitalization, and despite heparin infusion she experienced myocardial infarction (MI), caused by embolic occlusion of the left anterior descending artery. Although infrequent as a complication of LVNC, and usually attributable to microvascular dysfunction, in this case MI seems due to coronary thromboembolism from dislodged thrombotic material in the left ventricle.

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