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Serum visfatin and omentin levels in slow coronary flow
Author(s) -
Taner Uçgun,
Cengiz Başar,
Ramazan Memişoğulları,
Hilmi Demirin,
Yasin Türker,
Yusuf Aslantaş
Publication year - 2014
Publication title -
revista portuguesa de cardiologia
Language(s) - English
Resource type - Journals
eISSN - 2174-2030
pISSN - 0870-2551
DOI - 10.1016/j.repc.2014.04.007
Subject(s) - adipokine , medicine , timi , coronary artery disease , cardiology , proinflammatory cytokine , pathophysiology , inflammation , endothelial dysfunction , endocrinology , pathogenesis , adiponectin , gastroenterology , myocardial infarction , leptin , obesity , insulin resistance , thrombolysis
The adipocytokines visfatin and omentin have a direct effect on inflammation and endothelial injury. The expression of visfatin is closely associated with the expression of proinflammatory cytokines. Omentin has an anti-inflammatory effect and is inversely associated with coronary artery disease (CAD). The slow coronary flow phenomenon is an angiographic finding characterized by delayed distal vessel opacification in the absence of significant epicardial coronary disease. The pathophysiology of SCF has not been clearly identified, although multiple abnormalities including endothelial dysfunction, atherothrombosis and inflammation have been reported. However, the relationship between visfatin, omentin and SCF is still unknown. In this study, we aimed to investigate the relationship of these adipocytokines with SCF.

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