Functional assessment of coronary artery disease by intravascular ultrasound and computational fluid dynamics simulation | Zendy

Sebastián Carrizo | Zendy; Xinzhou Xie | Zendy; Rafaél Peinado | Zendy; Ángel SánchezRecalde | Zendy; Santiago JiménezValero | Zendy; Guillermo Galeote-García | Zendy; Raúl Moreno | Zendy

Open Access

Functional assessment of coronary artery disease by intravascular ultrasound and computational fluid dynamics simulation

Author(s) -

Sebastián Carrizo,

Xinzhou Xie,

Rafaél Peinado,

Ángel SánchezRecalde,

Santiago JiménezValero,

Guillermo Galeote-García,

Raúl Moreno

Publication year - 2014

Publication title -

revista portuguesa de cardiologia

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.266

H-Index - 26

eISSN - 2174-2030

pISSN - 0870-2551

DOI - 10.1016/j.repc.2014.03.013

Subject(s) - intravascular ultrasound , fractional flow reserve , cardiology , medicine , conventional pci , percutaneous coronary intervention , computational fluid dynamics , coronary artery disease , stenosis , coronary angiography , radiology , myocardial infarction , engineering , aerospace engineering

Clinical trials have shown that functional assessment of coronary stenosis by fractional flow reserve (FFR) improves clinical outcomes. Intravascular ultrasound (IVUS) complements conventional angiography, and is a powerful tool to assess atherosclerotic plaques and to guide percutaneous coronary intervention (PCI). Computational fluid dynamics (CFD) simulation represents a novel method for the functional assessment of coronary flow. A CFD simulation can be calculated from the data normally acquired by IVUS images. A case of coronary heart disease studied with FFR and IVUS, before and after PCI, is presented. A three-dimensional model was constructed based on IVUS images, to which CFD was applied. A discussion of the literature concerning the clinical utility of CFD simulation is provided.

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