Highly Sensitive Electrospun Multiwalled Carbon Nanotubes Embedded Zinc Oxide Nanowire Based Interface for Label Free Biosensing
Author(s) -
K. Brince Paul,
Siva Rama Krishna Vanjari,
Shiv Govind Singh
Publication year - 2017
Publication title -
procedia technology
Language(s) - English
Resource type - Journals
ISSN - 2212-0173
DOI - 10.1016/j.protcy.2017.04.091
Subject(s) - materials science , nanowire , surface modification , nanotechnology , carbon nanotube , electrospinning , biosensor , biocompatibility , streptavidin , zinc , electrochemistry , graphene , composite number , chemical engineering , electrode , composite material , polymer , chemistry , biotin , biochemistry , engineering , metallurgy
We demonstrate synthesis of Multiwalled carbon nanotubes (MW\udCNTs) embedded highly oriented Zinc Oxide (ZnO) nanowires \udtargeted towards development of ultrasen\udsitive electrochemical nanobiosensors using \udelectrospinning method. The synthesized \udcomposite nanowires combines advantages of ZnO such as biocompa\udtibility, electrostatic affinity towards biomolecules with the \udexcellent conductivity and surface functi\udonalization capabilities of MWCNTs. Calcinatio\udn temperature is optimized so as to \udensure MWCNTs are present in their original form and at the same\ud time highly crystalline ZnO is obtained. The key advantage o f \udthis process is that there is no separate functionalization pr\udocess is required to create functional groups on MWCNTs. \udFurthermore, the electrochemical activity of MWCNTs embedded ZnO nanowires is much higher as compared to pure ZnO \udnanowires. We have demonstrated the performance of electrochem\udical nanobiosensor using Biotin\ud-streptavidin interaction as \udmodel system. The sensor exhibits excellent sensitivity in the range 10 μ gmL\ud-1\ud - 0.5 fgmL\ud-1\ud of streptavidin with 0.5fgmL\ud-1\ud limit \udof detection
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