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Complex Data-driven Predictive Modeling in Personalized Clinical Decision Support for Acute Coronary Syndrome Episodes
Author(s) -
Alexey V. Krikunov,
Ekaterina Bolgova,
Evgeniy Krotov,
Tesfamariam M. Abuhay,
A. N. Yakovlev,
Sergey V. Kovalchuk
Publication year - 2016
Publication title -
procedia computer science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.334
H-Index - 76
ISSN - 1877-0509
DOI - 10.1016/j.procs.2016.05.332
Subject(s) - computer science , acute coronary syndrome , clinical decision support system , decision support system , predictive modelling , classifier (uml) , data mining , machine learning , decision model , artificial intelligence , data modeling , medicine , database , myocardial infarction
The objective of this paper is to demonstrate the development of complex model of clinical episode, based on data-driven approach, for decision support in treatment of ACS (Acute Coronary Syndrome). The idea is aimed at improving predictive capability of a data-driven model by combining different models within a composite data-driven model. It can be implemented either hierarchical or alternative combination of models. Three examples of data-driven models are described: simple classifier, outcome prediction based on reanimation time and states-based prediction model, to be used as part of complex model of episodes. To implement the proposed approach, a generalized architecture of data-driven clinical decision support systems was developed. The solution is developed as a part of complex clinical decision support system for cardiac diseases for Federal Almazov North-West Medical Research Centre in Saint Petersburg, Russia

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