Detection of ligand-elicited cellular responses using Surface Acoustic Wave biosensors | Zendy

Shrey Pathak | Zendy; Melissa Jordan | Zendy; Zoltán Rácz | Zendy; R. A. John Challiss | Zendy; Julian W. Gardner | Zendy; Marina Cole | Zendy

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Detection of ligand-elicited cellular responses using Surface Acoustic Wave biosensors

Author(s) -

Shrey Pathak,

Melissa Jordan,

Zoltán Rácz,

R. A. John Challiss,

Julian W. Gardner,

Marina Cole

Publication year - 2011

Publication title -

procedia computer science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.334

H-Index - 76

ISSN - 1877-0509

DOI - 10.1016/j.procs.2011.09.073

Subject(s) - biosensor , sf9 , surface acoustic wave , neurotransmitter receptor , neurotransmitter , computer science , ligand (biochemistry) , receptor , biophysics , materials science , nanotechnology , chemistry , biology , acoustics , gene , biochemistry , physics , recombinant dna , spodoptera

Here, we present the design and development of a novel Surface Acoustic Wave (SAW) biosensor system and report preliminary results using a functionalised coating (Sf9 whole cells), to detect secondary cellular responses triggered when 12.5 μM of octopamine hydrochloride, an invertebrate neurotransmitter, binds to its endogenously expressed receptors present within the cell plasma membrane.

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