Melanoma Volatile Fingerprint with a Gas Sensor Array: In Vivo and In Vitro Study
Author(s) -
Giorgio Pennazza,
Marco Santonico,
Armando Bartolazzi,
Martinelli,
Roberto Paolesse,
Corrado Di Natale,
R. Bono,
Vincenzopio Tamburrelli,
S. Cristina,
A. D’Amico
Publication year - 2009
Publication title -
procedia chemistry
Language(s) - English
Resource type - Journals
ISSN - 1876-6196
DOI - 10.1016/j.proche.2009.07.248
Subject(s) - melanoma , human skin , fingerprint (computing) , masking (illustration) , in vitro , reproducibility , in vivo , chemistry , biomedical engineering , chromatography , computer science , biology , medicine , cancer research , artificial intelligence , biochemistry , art , genetics , microbiology and biotechnology , visual arts
Volatile compounds fingerprinting with gas sensor arrays is a promising non-invasive methodology for human health-state monitoring. Anyway, the large variability of human samples (breath, urine, sweat, skin transpiration) may have a complex influence in the composition of the volatile part and in the reproducibility of the analyses. Nonetheless, skin analysis is a favourable application where each subject can provide its own reference: free skin portions compared with skin lesions, avoiding the masking effects of skin volatiles composition variability. Moreover, in vitro measurements of melanoma cell lines show that enough information to recognize different tumor-types can be obtained by cells headspace
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