Next-generation microfluidic lab-on-a-chip platforms for point-of-care diagnostics and systems biology | Zendy

Jens Ducrée | Zendy

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Next-generation microfluidic lab-on-a-chip platforms for point-of-care diagnostics and systems biology

Author(s) -

Jens Ducrée

Publication year - 2009

Publication title -

procedia chemistry

Language(s) - English

Resource type - Journals

ISSN - 1876-6196

DOI - 10.1016/j.proche.2009.07.129

Subject(s) - microfluidics , lab on a chip , point of care , nanotechnology , chip , microfluidic chip , materials science , computer science , process engineering , biochemical engineering , engineering , medicine , telecommunications , pathology

Lab-on-a-chip technologies have pervaded various fields of the life sciences including nucleic acid testing, immunoassays and cell screening. It has by now been clearly recognized that microfluidic liquid handling offers a unique approach to integrate, automate, parallelize and miniaturize assay formats, thus making it possible to port them from the lab bench to point of care settings. In systems biology, the interaction of cells with micromachined, scale-matched features also offers a new access to the cellular world. This presentation will survey a set of novel microfluidic lab-on-a-chip platforms in the fields of point-of-care diagnostics and systems biology. Important design parameters are low-complexity instrumentation and the amenability of the usually disposable cartridge for high volume polymer microfabrication

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