Impact of neoadjuvant androgen deprivation therapy on magnetic resonance imaging features in prostate cancer before radiotherapy
Author(s) -
Ulrika Björeland,
Tufve Nyholm,
Joakim Jönsson,
Mikael Skorpil,
Lennart Blomqvist,
Sara Strandberg,
Katrine Riklund,
L. Beckman,
Camilla ThellenbergKarlsson
Publication year - 2021
Publication title -
physics and imaging in radiation oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.777
H-Index - 12
ISSN - 2405-6316
DOI - 10.1016/j.phro.2021.01.004
Subject(s) - prostate cancer , medicine , androgen deprivation therapy , magnetic resonance imaging , radiation therapy , prostate , effective diffusion coefficient , prostatectomy , nuclear medicine , urology , cancer , radiology
In locally advanced prostate cancer (PC), androgen deprivation therapy (ADT) in combination with whole prostate radiotherapy (RT) is the standard treatment. ADT affects the prostate as well as the tumour on multiparametric magnetic resonance imaging (MRI) with decreased PC conspicuity and impaired localisation of the prostate lesion. Image texture analysis has been suggested to be of aid in separating tumour from normal tissue. The aim of the study was to investigate the impact of ADT on baseline defined MRI features in prostate cancer with the goal to investigate if it might be of use in radiotherapy planning.
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