Redistributed versus homogenous radiotherapy dose for head and neck cancer; a treatment planning study | Zendy

Jolien Heukelom | Zendy; Emmy Lamers | Zendy; E. van Slooten | Zendy; Erik van Werkhoven | Zendy; C. Rasch | Zendy; JanJakob Sonke | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Redistributed versus homogenous radiotherapy dose for head and neck cancer; a treatment planning study

Author(s) -

Jolien Heukelom,

Emmy Lamers,

E. van Slooten,

Erik van Werkhoven,

C. Rasch,

JanJakob Sonke

Publication year - 2017

Publication title -

physics and imaging in radiation oncology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.777

H-Index - 12

ISSN - 2405-6316

DOI - 10.1016/j.phro.2017.07.002

Subject(s) - medicine , head and neck cancer , radiation therapy , head and neck squamous cell carcinoma , radiation treatment planning , nuclear medicine , positron emission tomography , radiology

Dose redistribution, where radio-resistant parts of the tumour are boosted while the border of the planning target volume receives a lower dose has the potential to increase local control in advanced head and neck squamous cell carcinoma (HNSCC). In this treatment planning study for 20 patients, standard radiotherapy (RT) of 70 Gy, was compared to redistributed RT following the ARTFORCE trial protocol (NCT01504815), i.e., a fluorodeoxyglucose-positron emission tomography (FDG-PET) based heterogeneous simultaneous-integrated-boost to a total dose of 64–84 Gy. Redistribution marginally increased the mean ipsilateral ⧹contralateral parotid dose by 1.55⧹0.55 Gy but not dose to other organs at risk

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research