Open AccessSingle strain versus multispecies probiotic on necrotizing enterocolitis and faecal IgA levels in very low birth weight preterm neonates: A randomized clinical trial
Author(s) -
Guadalupe Gómez–Rodríguez,
Norma AmadorLicona,
Leonel Daza-Benítez,
Gloria BarbosaSabanero,
Deyanira Carballo-Magdaleno,
Rodrigo Aguilar-Padilla,
Eduardo González-Ramirez
Publication year - 2019
Publication title -
pediatrics and neonatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.569
H-Index - 36
eISSN - 2212-1692
pISSN - 1875-9572
DOI - 10.1016/j.pedneo.2019.02.005
Subject(s) - necrotizing enterocolitis , probiotic , medicine , lactobacillus acidophilus , gestational age , incidence (geometry) , randomized controlled trial , neonatal intensive care unit , birth weight , immunoglobulin a , gastroenterology , pregnancy , immunology , biology , antibody , pediatrics , immunoglobulin g , genetics , physics , bacteria , optics
According to the literature, probiotics are an attractive alternative to prevent necrotizing enterocolitis (NEC). However, due to differences in probiotic composition, randomized controlled trials are necessary to compare different probiotic mixtures. The objective of this study was to compare single strain (Lactobacillus acidophilus boucardii) versus multispecies probiotics on NEC incidence and faecal secretory Immunoglobulin A (sIgA) levels in very low preterm newborns.
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