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A Learning-Based Model to Evaluate Hospitalization Priority in COVID-19 Pandemics
Author(s) -
Y.K. Zheng,
Yinheng Zhu,
Mengqi Ji,
Rongpin Wang,
Xinfeng Liu,
Mudan Zhang,
Jun Liu,
Xiaochun Zhang,
Choo Hui Qin,
Lu Fang,
Shaohua Ma
Publication year - 2020
Publication title -
patterns
Language(s) - English
Resource type - Journals
ISSN - 2666-3899
DOI - 10.1016/j.patter.2020.100092
Subject(s) - pandemic , covid-19 , medicine , disease , severity of illness , intensive care medicine , health care , hospital admission , lactate dehydrogenase , emergency medicine , medical emergency , virology , infectious disease (medical specialty) , outbreak , biology , biochemistry , economics , enzyme , economic growth
The emergence of novel coronavirus disease 2019 (COVID-19) is placing an increasing burden on the healthcare systems. Although the majority of infected patients have non-severe symptoms and can be managed at home, some individuals may develop severe disease and are demanding the hospital admission. Therefore, it becomes paramount to efficiently assess the severity of COVID-19 and identify hospitalization priority with precision. In this respect, a 4-variable assessment model, including lymphocyte, lactate dehydrogenase (LDH), C-reactive protein (CRP) and neutrophil, is established and validated using the XGBoost algorithm. This model is found effective to identify severe COVID-19 cases on admission, with a sensitivity of 84.6%, a specificity of 84.6%, and an accuracy of 100% to predict the disease progression toward rapid deterioration. It also suggests that a computation-derived formula of clinical measures is practically applicable for the healthcare administrators to distribute hospitalization resources to the most needed in epidemics and pandemics.

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