RETRACTED: Calcium sensing receptor and heart diseases | Zendy

Weihua Zhang | Zendy; Changqing Xu | Zendy

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RETRACTED: Calcium sensing receptor and heart diseases

Author(s) -

Weihua Zhang,

Changqing Xu

Publication year - 2009

Publication title -

pathophysiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.758

H-Index - 50

eISSN - 1873-149X

pISSN - 0928-4680

DOI - 10.1016/j.pathophys.2009.02.013

Subject(s) - endoplasmic reticulum , microbiology and biotechnology , calcium in biology , calcium , receptor , intracellular , cardiac myocyte , second messenger system , calcium sensing receptor , extracellular , fas ligand , calcium signaling , myocyte , inositol trisphosphate receptor , biology , endocrinology , chemistry , medicine , inositol , apoptosis , calcium metabolism , biochemistry , programmed cell death

Calcium ion is the first identified endogenous substance to function as both a first and second messenger via the stimulation of an extracellular calcium sensing receptor (CaR). CaR is a seven transmembrane G-protein-coupled receptor, which activates intracellular effectors, for example, it causes inositol phosphate (IP) accumulation to increase the release of intracellular calcium. Furthermore, more and more evidence shows that CaR is related to mediating the cellular functions in various cells.

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