Open AccessA Meta‐Analysis of Biomarkers in Laryngeal Dysplasia
Author(s) -
Nankivell Paul,
Weller Matthew,
McConkey Christopher,
Mehanna Hisham
Publication year - 2010
Publication title -
otolaryngology–head and neck surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.232
H-Index - 121
eISSN - 1097-6817
pISSN - 0194-5998
DOI - 10.1016/j.otohns.2010.06.314
Subject(s) - meta analysis , dysplasia , medicine , quality of evidence , oncology , pathology
Conclusion • Currently there is insufficient good quality evidence for the routine use of biomarkers in predicting the future behaviour of laryngeal dysplastic lesions • Only three studies (on p53, Cortacin/cyclin D1 and Ki67) showed statistically significant results • Better reporting of studies using the REMARK consensus guidelines should help to improve this in the future A Meta-Analysis of Biomarkers in Laryngeal Dysplasia