Diffusion and Monod kinetics model to determine in vivo human corneal oxygen-consumption rate during soft contact lens wear | Zendy

L. F. del Castillo | Zendy; Ana R. Ferreira da Silva | Zendy; S. I. Hernández | Zendy; María José Gómez Aguilella | Zendy; Andreu Andrio | Zendy; Sergio Mollá | Zendy; Vicente Compañ | Zendy

Open Access

Diffusion and Monod kinetics model to determine in vivo human corneal oxygen-consumption rate during soft contact lens wear

Author(s) -

L. F. del Castillo,

Ana R. Ferreira da Silva,

S. I. Hernández,

María José Gómez Aguilella,

Andreu Andrio,

Sergio Mollá,

Vicente Compañ

Publication year - 2014

Publication title -

journal of optometry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.844

H-Index - 25

eISSN - 1888-4296

pISSN - 1989-1342

DOI - 10.1016/j.optom.2014.06.002

Subject(s) - cornea , contact lens , oxygen , oxygen permeability , partial pressure , oxygen tension , ophthalmology , diffusion , chemistry , materials science , analytical chemistry (journal) , thermodynamics , physics , medicine , chromatography , organic chemistry

We present an analysis of the corneal oxygen consumption Qc from non-linear models, using data of oxygen partial pressure or tension (P(O2) ) obtained from in vivo estimation previously reported by other authors. (1) METHODS: Assuming that the cornea is a single homogeneous layer, the oxygen permeability through the cornea will be the same regardless of the type of lens that is available on it. The obtention of the real value of the maximum oxygen consumption rate Qc,max is very important because this parameter is directly related with the gradient pressure profile into the cornea and moreover, the real corneal oxygen consumption is influenced by both anterior and posterior oxygen fluxes.

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