MP76-12 REGULAR LOW DOSE SILDENAFIL REDUCES VENOUS LEAK RATES AFTER RADICAL PROSTATECTOMY

days preceding visits. Quality of life (QoL) was assessed by the SF36 questionnaire at Weeks 1 and 52 (end of study). RESULTS: Hypogonadal subjects with SD were significantly older (p1⁄40.001), and had lower serum estradiol levels (p1⁄40.043); baseline T levels were not significantly different. Sexual desire and activity, which were similar in both groups at baseline, improved to a similar extent in each group. In men with and without SD, LPCN 1021 significantly improved penile rigidity (p<0.001 and p1⁄40.028, respectively) and ability to maintain an erection (p<0.001 and p1⁄40.007, respectively). Non-significant differences were observed for the same with T gel 1.62%. In addition, LPCN 1021 significantly improved depressed mood (p1⁄40.002), mental health (p1⁄40.023) and mental component summary (p1⁄40.008) in hypogonadal subjects with SD. CONCLUSIONS: Conclusions: Twice daily administration of oral LPCN 1021 over 52 weeks improved several parameters of sexual function in hypogonadal men with SD prior to treatment. 1Cunningham GR, et al. J Clin Endocrinol Metab. 2015 Mar;100(3):1146-55.