Synthesis and biological evaluation of new sydnone based derivatives | Zendy

Yogesh M. Patel | Zendy; Keshav Patel | Zendy

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Synthesis and biological evaluation of new sydnone based derivatives

Author(s) -

Yogesh M. Patel,

Keshav Patel

Publication year - 2012

Publication title -

journal of saudi chemical society

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.67

H-Index - 47

eISSN - 2212-4640

pISSN - 1319-6103

DOI - 10.1016/j.jscs.2012.02.005

Subject(s) - sydnone , chalcone , elemental analysis , chemistry , pyrimidine , spectroscopy , carbon 13 nmr , organic chemistry , stereochemistry , combinatorial chemistry , physics , ring (chemistry) , quantum mechanics

An extensive characterization study on the novel series of synthesized sydnone, chalcone and pyrimidine is reported in this paper. A series of 3-(4-chlorophenyl)-4-{[4-(3-substitutedphenylacryloyl)phenyl]sulfamoyl}-sydnone and 3-(4-chlorophenyl)-4-[4-(4-aminophenyl)-6-substitutedphenylpyrimidin-2-aminesulfonyl]-sydnone are synthesized. The structures of the synthesized compounds were characterized by elemental analysis, IR, 1H NMR, 13C NMR and mass spectroscopy. An exclusive study on microbial activity using various microbial strains was also undertaken to support and confirm our experimental findings

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