The solubility parameter for biomedical polymers—Application of inverse gas chromatography
Author(s) -
Katarzyna Adamska,
Adam Voelkel,
A. Berlińska
Publication year - 2016
Publication title -
journal of pharmaceutical and biomedical analysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.777
H-Index - 127
eISSN - 1873-264X
pISSN - 0731-7085
DOI - 10.1016/j.jpba.2016.04.014
Subject(s) - inverse gas chromatography , solubility , polylactic acid , miscibility , hildebrand solubility parameter , chemistry , polymer , polycaprolactone , polyethylene glycol , gas chromatography , solvent , chromatography , flory–huggins solution theory , chemical engineering , organic chemistry , engineering
The solubility parameter seems to be a useful tool for thermodynamic characterisation of different materials. The solubility parameter concept can be used to predict sufficient miscibility or solubility between a solvent and a polymer, as well as components of co-polymer matrix in composite biomaterials. The values of solubility parameter were determined for polycaprolactone (PCL), polylactic acid (PLA) and polyethylene glycol (PEG) by using different procedures and experimental data, collected by means of inverse gas chromatography.
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