Mullite cytotoxicity and cell adhesion studies | Zendy

Leandro Fernandes | Zendy; Renata Aquino de Carvalho | Zendy; André Capaldo Amaral | Zendy; Édison Pécoraro | Zendy; Rafael Salomão | Zendy; Eliane Trovatti | Zendy

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Mullite cytotoxicity and cell adhesion studies

Author(s) -

Leandro Fernandes,

Renata Aquino de Carvalho,

André Capaldo Amaral,

Édison Pécoraro,

Rafael Salomão,

Eliane Trovatti

Publication year - 2019

Publication title -

journal of materials research and technology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.832

H-Index - 44

eISSN - 2214-0697

pISSN - 2238-7854

DOI - 10.1016/j.jmrt.2019.04.001

Subject(s) - mullite , materials science , biocompatibility , flexural strength , ceramic , sintering , adhesion , composite material , cytotoxicity , metallurgy , in vitro , chemistry , biochemistry

Mullite is a low cost ceramic material based on aluminous silicate and synthesized via solid state reaction. Mullite displays potential properties for application in the biomedical field, specially its high mechanical strength, however it is poorly characterized with respect to its specific cytotoxicity and capability to allow the cell adhesion to its surface. Here, mullite was prepared by sintering the mixture of Al2O3 and SiO2 at 1500 °C and characterized. Its elastic modulus was 135 GPa and its flexural strength, 109 MPa. The study of the viability of GM07492 human cells in presence of mullite revealed the proliferation and adhesion of the cells on its surface, which is an indication of biocompatibility. Its good mechanical properties and cytocompatibility suggested that mullite can be used as an alternative material for biomedical applications and dentistry.

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