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Treatment of recurrent complicated urinary tract infections in children with vesicoureteral reflux
Author(s) -
Tsung-Hua Wu,
FangLiang Huang,
LinShien Fu,
Chia-Man Chou,
Ya-Li Chien,
ChungMing Huang,
Chin-Fu Lin,
PoYen Chen
Publication year - 2014
Publication title -
journal of microbiology immunology and infection
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.223
H-Index - 57
eISSN - 1995-9133
pISSN - 1684-1182
DOI - 10.1016/j.jmii.2014.08.024
Subject(s) - medicine , vesicoureteral reflux , fosfomycin , cefazolin , urinary system , ceftazidime , amikacin , incidence (geometry) , cefotaxime , antimicrobial , antibiotics , medical record , pediatrics , reflux , pseudomonas aeruginosa , microbiology and biotechnology , disease , biology , genetics , physics , optics , bacteria
Urinary tract infections (UTIs) in children with vesicoureteral reflux (VUR) are often caused by uropathogens with a high rate of drug resistance and are associated with a high rate of recurrence with a single pathogen. In this study, we evaluated the incidence of recurrent UTI and the drug resistance pattern of Escherichia coli in children with VUR. We also evaluated whether combination therapy comprising fosomycin plus one other antimicrobial agent is effective for treatment of recurrent UTIs.

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