Open AccessConformational flexibility of apolipoprotein A-I amino- and carboxy-termini is necessary for lipid binding but not cholesterol efflux
Author(s) -
Shimpi Bedi,
Jamie Morris,
Amy Shah,
Rachel C. Hart,
W. Gray Jerome,
Stephen G. Aller,
Chongren Tang,
Tomas Vaisar,
Karin E. Bornfeldt,
Jere P. Segrest,
Jay W. Heinecke,
W. Sean Davidson
Publication year - 2022
Publication title -
journal of lipid research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.992
H-Index - 192
eISSN - 1539-7262
pISSN - 0022-2275
DOI - 10.1016/j.jlr.2022.100168
Subject(s) - chemistry , apolipoprotein b , phospholipid , efflux , mutant , biochemistry , cysteine , cholesterol , conformational change , serine , apolipoprotein a1 , biophysics , transporter , alanine , reverse cholesterol transport , protein structure , lipoprotein , plasma protein binding , atp binding cassette transporter 1 , peptide sequence , lipid bilayer , abca1 , protein–lipid interaction , stereochemistry
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