Burden of Middle East respiratory syndrome coronavirus infection in Saudi Arabia | Zendy

Rajaa AlRaddadi | Zendy; Omaima I. Shabouni | Zendy; Zeyad AlRaddadi | Zendy; Abdulmohsen H. AlZalabani | Zendy; Ahmad M. Al-Asmari | Zendy; Adel Ibrahim | Zendy; Abdullatif Almarashi | Zendy; Tariq A. Madani | Zendy

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Burden of Middle East respiratory syndrome coronavirus infection in Saudi Arabia

Author(s) -

Rajaa AlRaddadi,

Omaima I. Shabouni,

Zeyad AlRaddadi,

Abdulmohsen H. AlZalabani,

Ahmad M. Al-Asmari,

Adel Ibrahim,

Abdullatif Almarashi,

Tariq A. Madani

Publication year - 2019

Publication title -

journal of infection and public health

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.983

H-Index - 35

eISSN - 1876-035X

pISSN - 1876-0341

DOI - 10.1016/j.jiph.2019.11.016

Subject(s) - medicine , interquartile range , case fatality rate , middle east respiratory syndrome coronavirus , covid-19 , middle east respiratory syndrome , burden of disease , pediatrics , emergency medicine , health care , infection control , disease burden , mortality rate , disease , infectious disease (medical specialty) , epidemiology , intensive care medicine , economics , economic growth

MERS-coronavirus infection is currently responsible for considerable morbidity and mortality in Saudi Arabia. Understanding its burden, as an emerging infectious disease, is vital for devising appropriate control strategies. In this study, the burden of MERS-CoV was estimated over 31months period from June 6, 2012 to January 5, 2015. The total number of patients was 835; 528 (63.2%) patients were male, 771 (92.3%) patients were ≥25 years of age, and 210 (25.1%) patients were healthcare workers. A total of 751 (89.9%) patients required hospitalization. The median duration between onset of illness and hospitalization was 2 days (interquartile range, 0-5). The median length of hospital stay was 14 days (IQR, 6-27). The overall case fatality rate was 43.1%. Basic reproductive number was 0.9. Being Saudi, non-healthcare workers, and age ≥65 years were significantly associated with higher mortality. In conclusion, MERS-CoV infection caused a substantial health burden in Saudi Arabia.

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