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Central Diabetes Insipidus in a Cat with Central Nervous System B Cell Lymphoma
Author(s) -
Christopher J Simpson,
Caroline Mansfield,
Marjorie Milne,
Priscilla J Hodge
Publication year - 2011
Publication title -
journal of feline medicine and surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.837
H-Index - 61
eISSN - 1532-2750
pISSN - 1098-612X
DOI - 10.1016/j.jfms.2011.07.005
Subject(s) - diabetes insipidus , medicine , lethargy , polyuria , polydipsia , central nervous system , lymphoma , endocrinology , optic chiasm , desmopressin , pathology , diabetes mellitus , anatomy , optic nerve
A 6-year-old male neutered cat presented with blindness, lethargy, polydipsia, hyposthenuria and severe hypernatraemia. Central diabetes insipidus was demonstrated by means of a low measured anti-diuretic hormone (ADH) concentration in the face of hypernatraemia, and clinical response to supplementation with desmopressin. Magnetic resonance imaging of the brain showed a discrete mass in the region of the hypothalamus. The cat was euthanased and post-mortem histological examination demonstrated B cell lymphoma involving the brain, optic nerves, urinary bladder wall and diaphragm. To the authors' knowledge, this case report is the first to describe central diabetes insipidus caused by central nervous system lymphoma in the cat.

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