Open AccessCholesterol-lowering effect of Aralia elata (Miq.) Seem via the activation of SREBP-2 and the LDL receptor
Author(s) -
KyungA Hwang,
Yu-Jin Hwang,
Jin Song
Publication year - 2017
Publication title -
journal of the chinese medical association
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.535
H-Index - 42
eISSN - 1728-7731
pISSN - 1726-4901
DOI - 10.1016/j.jcma.2017.06.007
Subject(s) - hyperlipidemia , cholesterol , ldl receptor , abca1 , sterol regulatory element binding protein , medicine , hmg coa reductase , reductase , endocrinology , coenzyme a , sterol , receptor , scavenger receptor , pharmacology , biochemistry , biology , enzyme , lipoprotein , gene , diabetes mellitus , transporter
Hyperlipidemia causes arteriosclerosis, a risk factor for coronary heart disease. Prevention of hyperlipidemia by improving dietary habits has recently attracted attention. In this regard, we investigated whether Aralia elata (Miq.) Seem (AE) extract inhibits hepatic cholesterol accumulation and modulate the cellular signaling pathway.
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