The prognosis outcome of oral squamous cell carcinoma using HIF-2α
Author(s) -
Elva Lim,
Chia-Chun Kuo,
HsiFeng Tu,
ChengChieh Yang
Publication year - 2017
Publication title -
journal of the chinese medical association
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.535
H-Index - 42
eISSN - 1728-7731
pISSN - 1726-4901
DOI - 10.1016/j.jcma.2017.06.005
Subject(s) - medicine , carcinogenesis , cancer , statistical significance , tissue microarray , biomarker , basal cell , immunohistochemistry , pathology , log rank test , angiogenesis , survival analysis , oncology , cancer research , biology , biochemistry
Hypoxia-induced factors (HIF) has a role in angiogenesis and regulate tumorigenesis of cancer cell. The HIF is the best-identified mechanism that shows imbalance between consumption and oxygen supply in progressing tumor. This study of HIF-2α expression in oral squamous cell carcinoma (OSCC) aimed to investigate the relationship of HIF-2α and pathology characteristics related to its clinical correlation.
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