Hepatoprotective effects of naturally fermented noni juice against thioacetamide-induced liver fibrosis in rats | Zendy

YiLing Lin | Zendy; HuiWen Lin | Zendy; YiChen Chen | Zendy; DengJye Yang | Zendy; Chien-Chun Li | Zendy; YuanYen Chang | Zendy

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Hepatoprotective effects of naturally fermented noni juice against thioacetamide-induced liver fibrosis in rats

Author(s) -

YiLing Lin,

HuiWen Lin,

YiChen Chen,

DengJye Yang,

Chien-Chun Li,

YuanYen Chang

Publication year - 2017

Publication title -

journal of the chinese medical association

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.535

H-Index - 42

eISSN - 1728-7731

pISSN - 1726-4901

DOI - 10.1016/j.jcma.2016.10.014

Subject(s) - thioacetamide , medicine , traditional medicine , fermentation , food science , liver fibrosis , pharmacology , fibrosis , biology

Excessive reactive oxygen species (ROS) can result in inflammation and cytokine secretion in the liver, and then activate hepatic stellate cells that cause the accumulation of extracellular matrix proteins, especially collagen, in liver tissue. Naturally fermented noni juice (NJ; Morinda citrifolia) has been used for decades as a nutraceutical in humans. In this study, we intended to examine if NJ can ameliorate ROS-induced liver fibrosis via a thioacetamide (TAA)-induced rat model.

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