Ang-(1–7) inhibited mitochondrial fission in high-glucose-induced podocytes by upregulation of miR-30a and downregulation of Drp1 and p53 | Zendy

Lianhuan Ma | Zendy; Chunlei Han | Zendy; Tao Peng | Zendy; Naie Li | Zendy; Bei Zhang | Zendy; Xiaowen Zhen | Zendy; Xiangdong Yang | Zendy

Open Access

Ang-(1–7) inhibited mitochondrial fission in high-glucose-induced podocytes by upregulation of miR-30a and downregulation of Drp1 and p53

Author(s) -

Lianhuan Ma,

Chunlei Han,

Tao Peng,

Naie Li,

Bei Zhang,

Xiaowen Zhen,

Xiangdong Yang

Publication year - 2016

Publication title -

journal of the chinese medical association

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.535

H-Index - 42

eISSN - 1728-7731

pISSN - 1726-4901

DOI - 10.1016/j.jcma.2016.08.006

Subject(s) - downregulation and upregulation , mitochondrial fission , western blot , apoptosis , mitochondrion , medicine , podocyte , endocrinology , chemistry , microbiology and biotechnology , biology , biochemistry , kidney , gene , proteinuria

The aim of this study was to investigate the possible effects of angiotensin-(1-7) [Ang-(1-7)] on podocytes and the mitochondrial signaling pathway in a high-glucose (HG) environment.

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