Association of serum interleukin-17 and interleukin-23 levels with disease activity in Chinese patients with ankylosing spondylitis | Zendy

WeiSheng Chen | Zendy; Yu-Sheng Chang | Zendy; KuanChia Lin | Zendy; Chien-Chih Lai | Zendy; Shu-Hung Wang | Zendy; Kai-Hung Hsiao | Zendy; Hui-Ting Lee | Zendy; MingHan Chen | Zendy; ChangYouh Tsai | Zendy; ChungTei Chou | Zendy

Open Access

Association of serum interleukin-17 and interleukin-23 levels with disease activity in Chinese patients with ankylosing spondylitis

Author(s) -

WeiSheng Chen,

Yu-Sheng Chang,

KuanChia Lin,

Chien-Chih Lai,

Shu-Hung Wang,

Kai-Hung Hsiao,

Hui-Ting Lee,

MingHan Chen,

ChangYouh Tsai,

ChungTei Chou

Publication year - 2012

Publication title -

journal of the chinese medical association

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.535

H-Index - 42

eISSN - 1728-7731

pISSN - 1726-4901

DOI - 10.1016/j.jcma.2012.05.006

Subject(s) - ankylosing spondylitis , basfi , basdai , medicine , erythrocyte sedimentation rate , pathogenesis , interleukin 23 , spondylitis , gastroenterology , interleukin 17 , immunology , disease , inflammation , psoriatic arthritis

Ankylosing spondylitis (AS) is a chronic arthritis with a pathogenesis which is not fully understood. A third subset of IL-17-producing T helper cells, called Th17 cells, has been discovered and characterized. We investigated whether IL-17 and IL-23, two Th17-related cytokines, play any roles in the pathogenesis of, and have any correlations with, disease activity and clinical manifestations in AS.

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