Investigation on signal transduction pathways after H1 receptor activated by histamine in C6 glioma cells: Involvement of phosphatidylinositol and arachidonic acid metabolisms | Zendy

Chin-Lu Tseng | Zendy; Jiann-Wu Wei | Zendy

Open Access

Investigation on signal transduction pathways after H1 receptor activated by histamine in C6 glioma cells: Involvement of phosphatidylinositol and arachidonic acid metabolisms

Author(s) -

Chin-Lu Tseng,

Jiann-Wu Wei

Publication year - 2012

Publication title -

journal of the chinese medical association

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.535

H-Index - 42

eISSN - 1728-7731

pISSN - 1726-4901

DOI - 10.1016/j.jcma.2012.02.014

Subject(s) - mepyramine , histamine , phosphatidylinositol , phospholipase c , inositol , arachidonic acid , second messenger system , histamine h1 receptor , inositol phosphate , biochemistry , phospholipase a2 , histamine receptor , inositol trisphosphate , histamine h4 receptor , phosphatidic acid , receptor , signal transduction , chemistry , biology , histamine h2 receptor , phospholipid , endocrinology , antagonist , enzyme , membrane

Information related to histamine-induced cellular responses in C6 glioma cells through second messenger pathways has not been fully studied, especially the involvement of arachidonic acid (AA) metabolism. In addition, specific labeled ligand binding to histamine receptor sites still needs to be clarified.

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