A single small dose of ketamine prevents lung injury following hepatic ischemia-reperfusion in rabbits
Author(s) -
Hao Shen,
Lu Jin,
Zhuang Xinliang,
Yachun Zhou
Publication year - 2011
Publication title -
journal of the chinese medical association
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.535
H-Index - 42
eISSN - 1728-7731
pISSN - 1726-4901
DOI - 10.1016/j.jcma.2011.06.011
Subject(s) - medicine , ketamine , saline , lung , inferior vena cava , reperfusion injury , anesthesia , tumor necrosis factor alpha , ischemia , urology
Previous studies demonstrated that large-dose ketamine alleviated lipopolysaccharide-induced lung injury. We investigated whether a single small dose of ketamine could attenuate lung injury induced by hepatic ischemia-reperfusion (HIR) and, if so its underlying mechanisms.
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