Kinetics and involvement of interleukin-17 in the outcome of peritonitis in nondiabetic patients undergoing peritoneal dialysis☆ | Zendy

HsinHui Wang | Zendy; Tzong-Yann Lee | Zendy; ChingYuang Lin | Zendy

Open Access

Kinetics and involvement of interleukin-17 in the outcome of peritonitis in nondiabetic patients undergoing peritoneal dialysis☆

Author(s) -

HsinHui Wang,

Tzong-Yann Lee,

ChingYuang Lin

Publication year - 2011

Publication title -

journal of the chinese medical association

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.535

H-Index - 42

eISSN - 1728-7731

pISSN - 1726-4901

DOI - 10.1016/j.jcma.2011.01.002

Subject(s) - medicine , peritoneal dialysis , peritonitis , outcome (game theory) , gastroenterology , intensive care medicine , mathematical economics , mathematics

Peritonitis is the most serious complication of peritoneal dialysis (PD). We previously showed that high levels of interleukin (IL)-12 and IL-18 in PD effluents (PDE) during the early phase of peritonitis correlated with a predominant Type 1 immune response and a favorable outcome in PD-related peritonitis. To further clarify the longitudinal changes of peritoneal immunity during PD-related peritonitis, we examined the kinetic production of IL-17 in PDE during peritonitis. The correlation between the IL-17 expression pattern and peritonitis outcome was analyzed.

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