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Long-range allostery mediates the regulation of plasminogen activator inhibitor-1 by cell adhesion factor vitronectin
Author(s) -
Kyle C. Kihn,
Elisa Marchiori,
Giovanni Spagnolli,
Alberto Boldrini,
Luca Terruzzi,
Daniel A. Lawrence,
Anne Gershenson,
Pietro Faccioli,
Patrick L. Wintrode
Publication year - 2022
Publication title -
journal of biological chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.361
H-Index - 513
eISSN - 1067-8816
pISSN - 0021-9258
DOI - 10.1016/j.jbc.2022.102652
Subject(s) - vitronectin , serpin , allosteric regulation , biophysics , plasminogen activator inhibitor 1 , molecular dynamics , chemistry , binding site , plasminogen activator , protein structure , conformational change , stereochemistry , crystallography , biochemistry , biology , integrin , cell , genetics , enzyme , computational chemistry , gene

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