An intrinsically disordered transcription activation domain increases the DNA binding affinity and reduces the specificity of NFκB p50/RelA
Author(s) -
Hannah E.R. Baughman,
Dominic Narang,
Wei Chen,
Amalia C. Villagrán Suárez,
Joon Lee,
Maxwell J. Bachochin,
Tristan R. Gunther,
Peter G. Wolynes,
Elizabeth A. Komives
Publication year - 2022
Publication title -
journal of biological chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.361
H-Index - 513
eISSN - 1067-8816
pISSN - 0021-9258
DOI - 10.1016/j.jbc.2022.102349
Subject(s) - dna , transcription factor , transcription (linguistics) , p50 , binding site , enhancer , microbiology and biotechnology , dna binding domain , hmg box , dna binding site , dna binding protein , chemistry , biology , biophysics , promoter , genetics , gene , gene expression , philosophy , linguistics
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