Open AccessIsoforms of GPR35 have distinct extracellular N-termini that allosterically modify receptor-transducer coupling and mediate intracellular pathway bias
Author(s) -
Hannes Schihada,
Thomas M. Klompstra,
Laura J. Humphrys,
Igor Červenka,
Shamim Dadvar,
Peter Kolb,
Jorge L. Ruas,
Gunnar Schulte
Publication year - 2022
Publication title -
journal of biological chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.361
H-Index - 513
eISSN - 1067-8816
pISSN - 0021-9258
DOI - 10.1016/j.jbc.2022.102328
Subject(s) - intracellular , extracellular , allosteric regulation , microbiology and biotechnology , chemistry , gene isoform , coupling (piping) , receptor , protein–protein interaction , biophysics , biology , biochemistry , gene , materials science , metallurgy
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