Open AccessThe conformational change of the protease inhibitor α2-macroglobulin is triggered by the retraction of the cleaved bait region from a central channel
Author(s) -
Seandean L. Harwood,
Khang Diep,
Nadia Sukusu Nielsen,
Kathrine Tejlgård Jensen,
Jan J. Enghild
Publication year - 2022
Publication title -
journal of biological chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.361
H-Index - 513
eISSN - 1067-8816
pISSN - 0021-9258
DOI - 10.1016/j.jbc.2022.102230
Subject(s) - cleavage (geology) , conformational change , proteases , serine , protein structure , biophysics , serine protease , chemistry , biochemistry , protease , biology , stereochemistry , enzyme , paleontology , fracture (geology)
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