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Clathrin adaptor AP-1–mediated Golgi export of amyloid precursor protein is crucial for the production of neurotoxic amyloid fragments
Author(s) -
Yunan C. Januário,
Jessica Eden,
Luan S. de Oliveira,
Raffaella De Pace,
Lucas Tavares,
Mara E. da Silva-Januário,
Vinícius B. Apolloni,
Elise L. Wilby,
Randolf Altmeyer,
Patricia V. Burgos,
Sônia A. L. Corrêa,
David C. Gershlick,
Luis L. P. daSilva
Publication year - 2022
Publication title -
journal of biological chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.361
H-Index - 513
eISSN - 1067-8816
pISSN - 0021-9258
DOI - 10.1016/j.jbc.2022.102172
Subject(s) - endosome , amyloid precursor protein , signal transducing adaptor protein , microbiology and biotechnology , alpha secretase , golgi apparatus , amyloid precursor protein secretase , clathrin , chemistry , p3 peptide , transport protein , intracellular , neurotoxicity , extracellular , protein precursor , biochemistry , alzheimer's disease , biology , endocytosis , cell , signal transduction , medicine , enzyme , disease , organic chemistry , toxicity

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