Conformational flexibility in carbapenem hydrolysis drives substrate specificity of the class D carbapenemase OXA-24/40
Author(s) -
Joshua M. Mitchell,
Cynthia M. June,
Vincent Baggett,
Beth C. Lowe,
James F. Ruble,
Robert A. Bonomo,
David A. Leonard,
R.A. Powers
Publication year - 2022
Publication title -
journal of biological chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.361
H-Index - 513
eISSN - 1067-8816
pISSN - 0021-9258
DOI - 10.1016/j.jbc.2022.102127
Subject(s) - ertapenem , meropenem , doripenem , imipenem , carbapenem , acinetobacter baumannii , acinetobacter , microbiology and biotechnology , chemistry , acinetobacter calcoaceticus , biology , antibiotics , antibiotic resistance , bacteria , genetics , pseudomonas aeruginosa
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