RyR2 disease mutations at the C-terminal domain intersubunit interface alter closed-state stability and channel activation
Author(s) -
Wenting Guo,
Jinhong Wei,
John Paul Estillore,
Lin Zhang,
Ruiwu Wang,
Bo Sun,
S.R. Wayne Chen
Publication year - 2021
Publication title -
journal of biological chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.361
H-Index - 513
eISSN - 1067-8816
pISSN - 0021-9258
DOI - 10.1016/j.jbc.2021.100808
Subject(s) - ryanodine receptor , ryanodine receptor 2 , endoplasmic reticulum , mutant , chemistry , gating , mutation , microbiology and biotechnology , biophysics , caffeine , biochemistry , biology , endocrinology , gene
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom