Open AccessExcess exogenous pyruvate inhibits lactate dehydrogenase activity in live cells in an MCT1-dependent manner
Author(s) -
Yi Rao,
Seth T. Gammon,
Margie N. Sutton,
Niki M. Zacharias,
Pratip K. Bhattacharya,
David PiwnicaWorms
Publication year - 2021
Publication title -
journal of biological chemistry
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 2.361
H-Index - 513
eISSN - 1067-8816
pISSN - 0021-9258
DOI - 10.1016/j.jbc.2021.100775
Subject(s) - glycolysis , monocarboxylate transporter , biochemistry , pyruvate dehydrogenase kinase , pyruvate dehydrogenase complex , lactate dehydrogenase a , pyruvate decarboxylation , pyruvic acid , extracellular , lactate dehydrogenase , chemistry , metabolism , pkm2 , citric acid cycle , biology , pyruvate kinase , transporter , enzyme , gene
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