Surface-assisted laser desorption/ionization mass spectrometry on titania nanotube arrays | Zendy

Chun-Yuan Lo | Zendy; Jia-Yi Lin | Zendy; WeiYu Chen | Zendy; Cheng-Tai Chen | Zendy; YuChie Chen | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Surface-assisted laser desorption/ionization mass spectrometry on titania nanotube arrays

Author(s) -

Chun-Yuan Lo,

Jia-Yi Lin,

WeiYu Chen,

Cheng-Tai Chen,

YuChie Chen

Publication year - 2008

Publication title -

journal of the american society for mass spectrometry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.961

H-Index - 127

eISSN - 1879-1123

pISSN - 1044-0305

DOI - 10.1016/j.jasms.2008.04.025

Subject(s) - chemistry , mass spectrometry , desorption , substrate (aquarium) , analytical chemistry (journal) , detection limit , surface enhanced laser desorption/ionization , matrix assisted laser desorption/ionization , chromatography , sample preparation in mass spectrometry , electrospray ionization , organic chemistry , oceanography , adsorption , geology

Titania nanotube arrays (NTA) generated from anodizing processes are tested as the substrate for surface-assisted laser desorption/ionization mass spectrometry (SALDI MS). The background generated from titania NTA is very low, making the approach suitable for the analysis of small molecules. The upper detectable mass is approximately 29 kDa. Homogeneous sample deposition leads to good shot-to-shot reproducibility and suitability for quantitative analysis. Additionally, phosphopeptides can be selectively trapped on the titania NTA substrate, as illustrated by simply depositing a tryptic digest of beta-casein followed by titania NTA SALDI MS analysis. The detection limit for small organics and peptides is in low fmol.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research