Open AccessTheoretical and experimental evaluation of the low m/z transmission of an electrodynamic ion funnel
Author(s) -
Jason S. Page,
Aleksey V. Tolmachev,
Keqi Tang,
Richard Smith
Publication year - 2006
Publication title -
journal of the american society for mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.961
H-Index - 127
eISSN - 1879-1123
pISSN - 1044-0305
DOI - 10.1016/j.jasms.2005.12.013
Subject(s) - funnel , ion , multipole expansion , chemistry , cutoff , amplitude , range (aeronautics) , transmission (telecommunications) , electrical conductor , atomic physics , ion trap , computational physics , cutoff frequency , analytical chemistry (journal) , physics , optics , electrical engineering , quantum mechanics , materials science , organic chemistry , chromatography , composite material , engineering
The transmission of ions at low m/z can often be either necessary for an application or problematic (e.g., when large numbers of low m/z ions consume a large fraction of an ion trap's capacity). The low m/z ion transmission limit of an electrodynamic ion funnel has been characterized using both experimental and theoretical approaches. A theoretical model is developed based on a series of infinite wire conductors that represent the ring electrodes of the ion funnel. Mathematical relationships for both low and high m/z cutoffs of the idealized two-dimensional system are derived. The low m/z cutoff is also evaluated through a series of experiments that show it is influenced by both the RF frequency and the DC electric field gradient. However, unlike multipole ion guides, there is no marked dependence of the low m/z cutoff on the RF amplitude, in agreement with theoretical results. With this new understanding, ion funnels can be designed and configured to better match the m/z range requirements for various applications.