Open AccessFragmentation studies on tetronasin by accurate-mass electrospray tandem mass spectrometry
Author(s) -
Tatiana Fonseca,
Norberto P. Lopes,
Paul J. Gates,
James Staunton
Publication year - 2004
Publication title -
journal of the american society for mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.961
H-Index - 127
eISSN - 1879-1123
pISSN - 1044-0305
DOI - 10.1016/j.jasms.2003.10.020
Subject(s) - carbocation , fragmentation (computing) , chemistry , tandem mass spectrometry , electrospray , mass spectrometry , ion , collision induced dissociation , tandem , analytical chemistry (journal) , computational chemistry , photochemistry , chromatography , organic chemistry , materials science , computer science , composite material , operating system
We report here the first full fragmentation study of tetronasin 1. Fragmentation was carried out by high-resolution ESI-CID-MS(n). The formulae of the fragment ions were determined by accurate mass measurements. It is demonstrated that the fragmentation routes observed derive essentially from a first loss of water via two different mechanisms. One minor route consists of a charge remote neutral loss and the second major route occurs via the formation of a carbocation. The fragments obtained from this carbocation were produced by subsequent complex neutral eliminations and the structures were inferred, in some cases, by carbocation stability.