A Novel, Scalable Liquid Array Platform | Zendy

Christopher D. Herold | Zendy; Bao T. Nguyen | Zendy; David M. Rothwarf | Zendy

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A Novel, Scalable Liquid Array Platform

Author(s) -

Christopher D. Herold,

Bao T. Nguyen,

David M. Rothwarf

Publication year - 2008

Publication title -

jala journal of the association for laboratory automation

Language(s) - English

Resource type - Journals

eISSN - 1540-2452

pISSN - 1535-5535

DOI - 10.1016/j.jala.2008.06.002

Subject(s) - multiplex , scalability , multiplexing , planar , flexibility (engineering) , throughput , computer science , nanotechnology , on demand , materials science , bioinformatics , telecommunications , mathematics , operating system , statistics , wireless , biology , multimedia

As a result of a rapidly increasing demand for accurate, cost-effective, and highly flexible multiplexed assay systems, the annual market for multiplex assays is currently billions of dollars and is expected to continue to grow exponentially. Presently, there exist two broad classes of surface-based multiplex platforms—those using fixed planar surfaces (fixed arrays) and those that are particle-based (liquid arrays). We present here a description of an “Arrayable Liquid Array” platform, based on Encoded Sortable Particle (ESP) technology that combines many of the advantages of fixed and liquid arrays. ESPs have significant advantages in throughput, scalability, mixing efficiency, and flexibility over existing liquid array platforms while also incorporating the detection and manufacturing benefits of fixed arrays.

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