Automated Solubility Determination Using a Customized Robotic System and a Turbidity Probe | Zendy

Christian Dinter | Zendy; Armin Schuetz | Zendy; Thorsten Blume | Zendy; Hilmar Weinmann | Zendy; Michael Harré | Zendy; Harribert Neh | Zendy

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Automated Solubility Determination Using a Customized Robotic System and a Turbidity Probe

Author(s) -

Christian Dinter,

Armin Schuetz,

Thorsten Blume,

Hilmar Weinmann,

Michael Harré,

Harribert Neh

Publication year - 2005

Publication title -

jala journal of the association for laboratory automation

Language(s) - English

Resource type - Journals

eISSN - 1540-2452

pISSN - 1535-5535

DOI - 10.1016/j.jala.2005.08.006

Subject(s) - solubility , turbidity , process engineering , aqueous solution , reagent , solvent , throughput , automation , chemistry , environmental science , chemical engineering , materials science , computer science , engineering , organic chemistry , mechanical engineering , geology , telecommunications , oceanography , wireless

In chemical development, broad knowledge of solubilities of all reactants, reagents, and products is important because these data are needed for cleaning operations of multipurpose equipment in pilot and production plants. A fully automated workflow on a high-throughput robotic system for determination of solid material solubility in different aqueous and organic solvents is described. Automated solid dispensing, weighing, and solvent addition are performed followed by direct measurement of turbidity with an integrated three-wavelength turbidity probe. Finally, a report is generated containing all solubility information of the solid in a clearly arranged manner. (JALA 2005;10:408–11)

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