A pragmatic stepped-wedge cluster randomized trial to evaluate the effectiveness and cost-effectiveness of active case finding for household contacts within a routine tuberculosis program, San Juan de Lurigancho, Lima, Peru | Zendy

Lena Shah | Zendy; Marlene Rojas Peña | Zendy; Oscar Mori | Zendy; Carlos Zamudio | Zendy; Jay S. Kaufman | Zendy; Larissa Otero | Zendy; Eduardo Gotuzzo | Zendy; Carlos Seas | Zendy; Timothy F. Brewer | Zendy

Open Access

A pragmatic stepped-wedge cluster randomized trial to evaluate the effectiveness and cost-effectiveness of active case finding for household contacts within a routine tuberculosis program, San Juan de Lurigancho, Lima, Peru

Author(s) -

Lena Shah,

Marlene Rojas Peña,

Oscar Mori,

Carlos Zamudio,

Jay S. Kaufman,

Larissa Otero,

Eduardo Gotuzzo,

Carlos Seas,

Timothy F. Brewer

Publication year - 2020

Publication title -

international journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.278

H-Index - 89

eISSN - 1878-3511

pISSN - 1201-9712

DOI - 10.1016/j.ijid.2020.09.034

Subject(s) - cluster (spacecraft) , active tuberculosis , cluster randomised controlled trial , case finding , tuberculosis , wedge (geometry) , medicine , randomized controlled trial , geography , surgery , computer science , mycobacterium tuberculosis , physics , pathology , programming language , optics

Active case finding (ACF) in household contacts of tuberculosis (TB) patients is now recommended for National TB Programs (NTP) in low- and middle-income countries. However, evidence supporting these recommendations remains limited. This study evaluates the effectiveness and cost-effectiveness of ACF for household contacts of TB cases in a large TB endemic district of Lima, Peru.

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