Multisystem Inflammatory Syndrome in Children (MIS-C) with COVID-19: Insights from simultaneous familial Kawasaki Disease cases | Zendy

Risa EbinaShibuya | Zendy; Ho Namkoong | Zendy; Yusuke Shibuya | Zendy; Nobuyuki Horita | Zendy

Open Access

Multisystem Inflammatory Syndrome in Children (MIS-C) with COVID-19: Insights from simultaneous familial Kawasaki Disease cases

Author(s) -

Risa EbinaShibuya,

Ho Namkoong,

Yusuke Shibuya,

Nobuyuki Horita

Publication year - 2020

Publication title -

international journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.278

H-Index - 89

eISSN - 1878-3511

pISSN - 1201-9712

DOI - 10.1016/j.ijid.2020.06.014

Subject(s) - kawasaki disease , covid-19 , medicine , etiology , disease , immunology , pathology , infectious disease (medical specialty) , artery , outbreak

Recently, an increasing number of SARS-CoV-2 patients with COVID-19 syndrome, which overlaps with Kawasaki Disease (KD), have been reported, supporting the suggestion that infection is one of the triggers of KD. We summarized the reports of simultaneous familial KD cases to better understand the etiopathogenesis of both KD and Multisystem Inflammatory Syndrome in Children (MIS-C) related to COVID-19. Here we discuss the etiology of these syndromes from the point of view of infection and genetic susceptibility.

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