Ineffectiveness of procalcitonin-guided antibiotic therapy in severely critically ill patients: A meta-analysis | Zendy

Fei Peng | Zendy; Wei Chang | Zendy; Jian-Feng Xie | Zendy; Qin Sun | Zendy; Hai-Bo Qiu | Zendy; Yi Yang | Zendy

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Ineffectiveness of procalcitonin-guided antibiotic therapy in severely critically ill patients: A meta-analysis

Author(s) -

Fei Peng,

Wei Chang,

Jian-Feng Xie,

Qin Sun,

Hai-Bo Qiu,

Yi Yang

Publication year - 2019

Publication title -

international journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.278

H-Index - 89

eISSN - 1878-3511

pISSN - 1201-9712

DOI - 10.1016/j.ijid.2019.05.034

Subject(s) - medicine , procalcitonin , antibiotics , intensive care unit , randomized controlled trial , cochrane library , subgroup analysis , confidence interval , meta analysis , antibiotic therapy , intensive care medicine , sepsis , microbiology and biotechnology , biology

Optimizing antibiotic therapy has an important impact on the management of critically ill patients. Procalcitonin (PCT) is considered to be of possible use in the guidance of antibiotic stewardship; however, its efficacy remains controversial. Thus, a meta-analysis was performed to determine the efficacy of PCT-guided antibiotic therapy in critically ill patients.

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