Candida Tropicalis renal microabscesses in a child with leukemia confirmed using nucleic acid amplification and recovery after prolonged antifungal and corticosteroid treatment | Zendy

Jaime S. Rosa Duque | Zendy; Kelvin KaiWang To | Zendy; Aks Chiang | Zendy; Gcf Chan | Zendy; Rosana WingShan Poon | Zendy; KwokYung Yuen | Zendy; Sy Ha | Zendy; Daniel KL Cheuk | Zendy

Open Access

Candida Tropicalis renal microabscesses in a child with leukemia confirmed using nucleic acid amplification and recovery after prolonged antifungal and corticosteroid treatment

Author(s) -

Jaime S. Rosa Duque,

Kelvin KaiWang To,

Aks Chiang,

Gcf Chan,

Rosana WingShan Poon,

KwokYung Yuen,

Sy Ha,

Daniel KL Cheuk

Publication year - 2019

Publication title -

international journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.278

H-Index - 89

eISSN - 1878-3511

pISSN - 1201-9712

DOI - 10.1016/j.ijid.2019.02.002

Subject(s) - corticosteroid , chemotherapy , candida tropicalis , nucleic acid , neutropenia , polymerase chain reaction , antifungal , biology , immunology , medicine , pathology , microbiology and biotechnology , gene , biochemistry

We report the first case of microabscesses detected by polymerase chain reaction (PCR) amplification of nucleic acid from ultrasound-guided aspirated fluid in a three-year old boy with acute lymphoblastic leukemia and febrile neutropenia during induction chemotherapy. Fever persisted despite effective antifungal treatment. The addition of corticosteroid therapy successfully controlled the suspected immune reconstitution inflammatory syndrome (IRIS). This case highlights the utility of PCR and adjunctive corticosteroid in the approach of Candida tropicalis renal microabscesses in leukemic patients undergoing chemotherapy.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research